Preheat your oven to 375°F. Line a 15x10-inch jelly roll pan with parchment paper and grease the parchment. Lay a clean kitchen towel on the counter and dust it generously with powdered sugar.
Using an electric mixer, beat the eggs and granulated sugar on high speed for 3-4 minutes, until the mixture is thick, pale, and has tripled in volume. Beat in the pumpkin puree and vanilla extract on low speed until combined.
In a separate bowl, whisk together the gluten free 1-to-1 baking flour, ground cinnamon, baking soda, ground ginger, ground nutmeg, and salt. Fold the dry ingredients into the pumpkin mixture with a spatula until just combined.
Spread the batter evenly into the prepared pan. Bake for 13-15 minutes, until the cake springs back when lightly pressed in the center and a toothpick comes out clean.
Immediately invert the hot cake onto the prepared powdered sugar towel. Peel off the parchment paper. Starting from a short end, gently roll the cake up together with the towel into a tight log. Place seam-side down and let it cool completely, about 1 hour.
While the cake cools, beat the softened cream cheese, powdered sugar, softened butter, and vanilla extract together with an electric mixer until smooth and fluffy, about 2-3 minutes.
Carefully unroll the cooled cake. Spread the cream cheese filling evenly over the entire surface, leaving a 1/2-inch border along the far short edge. Re-roll the cake gently without the towel this time, keeping it as tight as possible without cracking.
Wrap the pumpkin roll tightly in plastic wrap and refrigerate for at least 2 hours or overnight. Before serving, dust the top with additional powdered sugar and slice into 1-inch rounds.